
Khorana was born into a poor family in Raipur in Punjab. He attended Punjab University at Lahore and the University of Liverpool, England, on government scholarships.
He obtained his Ph.D. at Liverpool in 1948. He began research on nucleic acids during a fellowship at the University of Cambridge under Sir Alexander Todd. He held fellowships and professorships in Switzerland at the Swiss Federal Institute of Technology and the universities of British Columbia, Can. and Wisconsin; in 1971 he joined the faculty of the Massachusetts Institute of Technology.
Khorana continued research on nucleic acid synthesis and in 1970 prepared the first artificial copy of a yeast gene. He shared the Nobel Prize in Physiology or Medicine in 1968 with Marshall W. Nirenberg and Robert W. Holley for research that helped to show how the genetic components of the cell nucleus control the synthesis of proteins.
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